Aggregation equations and Patlak-Keller-Segel (PKS) models for chemotaxis with nonlinear diffusion are popular models for nonlocal aggregation phenomenon and are a source of a number of interesting mathematical problems in nonlinear PDE. The purpose of this work is twofold. First, we continue our previous work, which focused on nonlocal aggregation, modeled with a convolution. The goal was to unify the local and global theory of these convolution-type models, including the identification of a sharp critical mass; however, some cases involving unbounded domains were left open. In particular, the biologically relevant case was not treated. In this paper, we present an alternative proof of local existence, which now applies to for all $d \geq 2$ and give global results that were left open. The proof departs from previous work in that it uses a more direct and intuitive regularization that constructs approximate solutions on instead of on sequences of bounded domains. Second, this work develops the local, subcritical, and small data critical theory for a variety of Patlak-Keller-Segel models with spatially varying diffusion and decay rate of the chemo-attractant.

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