BaBar’s observation of significant deviations of the pion transition form factor (TFF) from the asymptotic expectation with GeV has brought a serious crisis to a fundamental picture established for such a simplest system by perturbative QCD, i.e. the dominance of collinear factorization at high momentum transfers for the pion TFF. We show that non-factorizable contributions due to open flavors in could be an important source that contaminates the pQCD asymptotic limit and causes such deviations with GeV. Within an effective Lagrangian approach, the non-factorizable amplitudes can be related to intermediate hadron loops, i.e. and etc, and their corrections to the and TFFs can be estimated.

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