Nuclei in dense matter are influenced by the medium. In the cluster mean field approximation, an effective Schr"odinger equation for the -particle cluster is obtained accounting for the effects of the surrounding medium, such as self-energy and Pauli blocking. Similar to the single-baryon states (free neutrons and protons), the light elements (, internal quantum state ) are treated as quasiparticles with energies $E_{A,\nu}(P; T, n_n,n_p)\vec PTn_n,n_p$ of neutrons and protons, respectively. We consider the composition and thermodynamic properties of nuclear matter at low densities. At low temperatures, quartetting is expected to occur. Consequences for different physical properties of nuclear matter and finite nuclei are discussed.

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