We study the representation theory of the Ding-Iohara algebra to find -analogues of the Alday-Gaiotto-Tachikawa (AGT) relations. We introduce the endomorphism of the Ding-Iohara algebra, having two parameters and . We define the vertex operator by specifying the permutation relations with the Ding-Iohara generators and in terms of . For the level one representation, all the matrix elements of the vertex operators with respect to the Macdonald polynomials are factorized and written in terms of the Nekrasov factors for the -theoretic partition functions as in the AGT relations. For higher levels , we present some conjectures, which imply the existence of the -analogues of the AGT relations.

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