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In this contribution, recent ALICE measurements of the production cross section of single electrons, single muons and open charmed mesons in proton-proton collisions at sqrt(s) = 7 TeV are reported. The data are compared to next-to-leading-order perturbative QCD calculations. First open charm signals in Pb-Pb collisions at sqrt(sNN) = 2.76 TeV are shown.

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