Perfect phylogeny consisting of determining the compatibility of a set of characters is known to be NP-complete. We propose in this article a conjecture on the necessary and sufficient conditions of compatibility: Given a set of -states full characters, there exists a function such that is compatible iff every set of characters of is compatible. Some previous work showed that , and . Gusfield et al. 09 conjectured that for any $r \ge 2f(4) \ge 5$ and then a closure operation for chordal sandwich graphs. The later problem is a common approach of perfect phylogeny. This operation can be the first step to simplify the problem before solving some particular cases , and determining the function .

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