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In generic holographic QCD, we find that baryons are bound to form a nucleus, and that its radius obeys the empirically-known mass number (A) dependence r A^{1/3} for large A. Our result is robust, since we use only a generic property of D-brane actions in string theory. We also show that nucleons are bound completely in a finite volume. Furthermore, employing a concrete holographic model (derived by Hashimoto, Iizuka, and Yi, describing a multi-baryon system in the Sakai-Sugimoto model), the nuclear radius is evaluated as O(1) x A^{1/3} [fm], which is consistent with experiments.

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