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Theories of flavor violation beyond the Standard Model typically suppose that the new contributions must be small, for example suppressed by Yukawa couplings, as in Minimal Flavor Violation. We show that this need not be true, presenting a case for flavor violation which maximally mixes the first and third generation flavors. As an example, we realize this scenario via new right-handed gauge bosons, which couple predominantly to the combinations (u,b)_R and (t,d)_R. We show that this new flavor violation could be responsible for several anomalies, focusing in particular on the B_d and B_s systems, and the Tevatron top forward-backward asymmetry.

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