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We present a deep spectroscopic search for CO emission in the dwarf irregular galaxy DDO154, which has an Oxygen abundance of only 1/20 the solar value. The observations were conducted in order to constrain the CO-to- conversion factor at low metallicity. No CO was detected, however, despite being one of the sensitive observations done towards galaxies of this type. We succeed in putting a strong lower limit on the conversion factor, at least 10 times the Galactic value. Our result supports previous studies which argue for a high conversion factor at low metallicity.

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