In this paper, first we study some Arens regularity properties of module actions. Let be a Banach and let and be the topological centers of the left module action and the right module action , respectively. We investigate some relationships between topological center of , with respect to the first Arens product and topological centers of module actions and . On the other hand, if has Mazure property and has the left , then , and so for a locally compact non-compact group with compact covering number , we have and . By using the Arens regularity of module actions, we study some cohomological groups properties of Banach algebra and we extend some propositions from Dales, Ghahramani, Gr{\o}nb{\ae}k and others into general situations and we investigate the relationships between some cohomological groups of Banach algebra . We obtain some results in Connes-amenability of Banach algebras, and so for every compact group , we conclude that . Suppose that is an amenable locally compact group. Then there is a Banach such as such that $Z^1(L^1(G),L^\infty(G))={L_{f}:~f\in L^\infty(G)}g\in L^1(G)L_f(g)=f.g$.

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