In recent years, PHENIX has studied many important observables related to heavy-flavor physics through their leptonic decay measurements including the invariant yield of electrons from nonphotonic sources, and prompt single muons, both of which are dominated by D and B mesons. Charm and beauty cross-sections were measured and compared through single lepton, and lepton-hadron correlations in p+p collisions at = 200 GeV. Observables for quarkonia production such as invariant yield and polarization were also measured in p+p collisions. In Au+Au collisions, preliminary results for the for single electrons and a 90% CL upper limit for the suppression of s were produced. And in +Au collisions, a preliminary study for production in different centrality ranges was extracted.

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