Using localization, matrix model and saddle-point techniques, we determine
exact behavior of circular Wilson loop in N=2 superconformal (quiver) gauge
theories. Focusing at planar and large t Hooft couling limits, we compare its asymptotic behavior with well-known exponential growth of Wilson loop in N=4 super Yang-Mills theory. For theory with gauge group SU(N) coupled to 2N fundamental hypermultiplets, we find that Wilson loop exhibits non-exponential growth -- at most, it can grow a power of t Hooft coupling. For theory with
gauge group SU(N) x SU(N) and bifundamental hypermultiplets, there are two
Wilson loops associated with two gauge groups. We find Wilson loop in untwisted
sector grows exponentially large as in N=4 super Yang-Mills theory. We then
find Wilson loop in twisted sector exhibits non-analytic behavior with respect
to difference of two t Hooft coupling constants. By letting one gauge coupling constant hierarchically larger/smaller than the other, we show that Wilson loops in the second type theory interpolate to Wilson loop in the first type theory. We infer implications of these findings from holographic dual description in terms of minimal surface of dual string worldsheet. We suggest intuitive interpretation that in both type theories holographic dual background must involve string scale geometry even at planar and large t Hooft coupling
limit and that new results found in the gauge theory side are attributable to
worldsheet instantons and infinite resummation therein. Our interpretation also
indicate that holographic dual of these gauge theories is provided by certain
non-critical string theories.

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