We study cosmological application of interacting holographic energy density in the framework of Brans-Dicke cosmology. We obtain the equation of state and the deceleration parameter of the holographic dark energy in a non-flat universe. As system’s IR cutoff we choose the radius of the event horizon measured on the sphere of the horizon, defined as . We find that the combination of Brans-Dicke field and holographic dark energy can accommodate crossing for the equation of state of holographic dark energy. When an interaction between dark energy and dark matter is taken into account, the transition of to phantom regime can be more easily accounted for than when resort to the Einstein field equations is made.

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