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We point out how, in certain models, the same combination of New Physics couplings occur in the amplitudes for both D0-anti-D0 mixing and the rare decays D0 -> l+l-. If the New Physics dominates and is responsible for the observed mixing, then a very simple correlation exists between the magnitudes of each; in fact the rates for the decay D0 -> l+l- are completely fixed by the mixing. Observation of D0 -> l+l- in excess of the Standard Model prediction could identify New Physics contributions to D0-anti-D0 mixing.

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