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The measurements of rare decays are highly sensitive to physics beyond the standard model. In this article limits on the branching ratios of the decays B0s -> mu+mu-, D0 -> mu+mu- and D+ -> pi+mu+mu- are presented. Furthermore the first measurement of the branching fraction and CP asymmetry of Lambda_b -> p pi- and Lambda_b -> p K- decays is described. Data samples with an integrated luminosity of up to 2/fb collected at the Tevatron ppbar-collider at sqrt(s)=1.96 TeV were used in these analyses. The results are consistent with the standard model predictions and tighten the constraints on new physics models.

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