We consider a class of non-trivial perturbations of the degenerate Ornstein-Uhlenbeck operator in . In fact we perturb both the diffusion and the drift part of the operator (say and ) allowing the diffusion part to be unbounded in . Assuming that the kernel of the matrix is invariant with respect to $x\in {\mathbb R}^Nx\in{\mathbb R}^N$ by the same , and developing a revised version of Bernstein’s method we prove that we can associate a semigroup of bounded operators (in the space of bounded and continuous functions) with the operator . Moreover, we provide several uniform estimates for the spatial derivatives of the semigroup both in isotropic and anisotropic spaces of (H"older-) continuous functions. Finally, we prove Schauder estimates for some elliptic and parabolic problems associated with the operator .

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