Fix an odd prime . Let be a compact -adic Lie group containing a closed, normal, pro- subgroup which is abelian and such that is isomorphic to the additive group of -adic integers . First we assume that is finite and compute the Whitehead group of the Iwasawa algebra, , of . We also prove some results about certain localisation of needed in Iwasawa theory. Let be a totally real number field and let be an admissible -adic Lie extension of with Galois group . The computation of the Whitehead groups are used to show that the Main Conjecture for the extension can be deduced from certain congruences between abelian -adic zeta functions of Delige and Ribet. We prove these congruences with certain assumptions on . This gives a proof of the Main Conjecture in many interesting cases such as $_p\rtimes

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