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The superfluid-insulator transition of bosons is strongly modified by the presence of Fermions. Through an imaginary-time path integral approach, we derive the self-consistent mean-field transition line, and account for both the static and the dynamic screening effects of the fermions. We find that an effect akin to the fermionic orthogonality catastrophe, arising from the fermionic screening fluctuations, suppresses superfluidity. We analyze this effect for various mixture parameters and temperatures, and consider possible signatures of the orthogonality catastrophe effect in other measurables of the mixture.

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