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We develop a theoretical model of the carious lesion progress caused by acids diffusing into the tooth enamel from the dental plaque. The acids react with static hydroxyapatite, which leads to demineralization of the enamel, and consequently to the development of the carious lesion. The model utilizes the diffusion-reaction equations with one static and one mobile reactant where the reaction term is proportional to the product of concentrations of acids and of mineral. The changes of concentrations are calculated approximately by means of a perturbation method. The analytical approximate solutions are compared with the numerical ones and experimental data.

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