We study exact fillings of Legendrians and contact manifolds using Floer theory of universal covers. We prove vanishing results on wrapped Floer homology of the universal cover and symplectic (co)homology with coefficients by using lifted versions of Ritter’s TQFT operations. We use these results to show that an exact Maslov zero Lagrangian filling of the standard Legendrian in any Liouville filling of is diffeomorphic to a ball in dimension at least 5. We show that the existence of a topological simple exact filling with vanishing symplectic homology for a dynamically convex contact manifold reveals information about homotopy groups of and We also strengthen a theorem of Zhou for ADC-contact manifolds as an application of universal covers.

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