We obtain topological obstructions to the existence of a complete Riemannian metric with uniformly positive scalar curvature on the interiors of certain 4-manifolds using Seiberg–Witten theory. In particular, no punctured blowups of a homotopy K3 manifold admit complete metrics of uniformly positive scalar curvature. Further, let be a compact oriented smooth manifold of dimension , , or . We show that if admits a complete metric of uniformly positive scalar curvature, then admits a positive scalar curvature metric with minimal boundary. In dimensions and , the metric may moreover be chosen to be a product near the boundary. In dimension 5, under additional hypotheses and after possibly changing the smooth structure on , one can likewise obtain a positive scalar curvature metric that is a product near the boundary.

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