Symmetry considerations in chirality-induced spin selectivity

The chirality-induced spin selectivity (CISS) effect, the coupling between structural chirality and electron spin polarization, has been experimentally observed across many diverse systems. However, despite extensive theoretical effort, a unified mechanistic understanding remains elusive. In this perspective, we demonstrate how some of the basic properties of the fascinating effects of CISS can be understood based on straightforward symmetry considerations commonly employed in fundamental particle physics. In particular, we show that CISS does not violate any fundamental symmetries including parity and time-reversal. By anchoring CISS within the universal language of symmetry, we offer a robust conceptual foundation for interpreting experiments and guiding future theoretical and experimental designs.