The classification of block-transitive 5-designs remains an open problem. The additional parameter condition that divides is called the Camina-Gagen condition. In this paper, we investigate block-transitive simple - designs satisfying the Camina-Gagen condition. Using the classification of finite -homogeneous permutation groups, we consider the affine and almost simple cases separately. We prove that no such design admits a block-transitive automorphism group of affine type. For the almost simple case, up to isomorphism, there are exactly two possibilities: a - design admitting PGL(2,11) as a block-transitive automorphism group and a - design admitting PGL(2,23) as a block-transitive automorphism group.

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