Transmission spectroscopy of rocky exoplanets orbiting late M dwarfs is limited by stellar contamination rather than photon noise. We present a framework for this contamination-dominated regime, fitting all transit epochs jointly with a Gaussian process per epoch for the time-varying stellar contamination and a single atmospheric model shared across epochs. We use pure CO, HO, and CH models scaled by their peak-to-trough amplitude, allowing us to measure how large a signal must be to be recovered. We calibrate this framework using injection-recovery tests and 17 archival JWST/PRISM transits of the airless sibling TRAPPIST-1 b to quantify the spurious signals that stellar contamination alone produces. Applied to four JWST/NIRSpec PRISM transits of TRAPPIST-1 c, our framework recovers injected CO signals without bias and reaches detection thresholds of 146 (171) ppm for moderate (strong) evidence, compared with 96 ppm if there were no stellar contamination. CO and CH produce no spurious signals on the airless control planet, whereas HO shows a persistent stellar floor of ppm. TRAPPIST-1 c is consistent with a featureless, airless baseline for all three molecules. Our 95 per cent upper limit of 90 ppm for CO-shaped signals effectively rules out clear, isothermal pure-CO atmospheres (0.1 bar) and N-dominated atmospheres with 1 per cent CO (1 bar) at the equilibrium temperature. An empirical scaling study using 2 to 10 transits of TRAPPIST-1 b shows the CO detection threshold decreasing with the number of transits as , reaching 80 ppm at ten transits, while water searches become limited by the stellar floor beyond about six transits. CO atmospheres, by contrast, are detectable when we utilize our framework to account for stellar activity at the cost of roughly 1.5 to 2 times as many transits.

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