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Let be a Hilbert C*-module and the C*-algebra of all bounded adjointable operators on . An operator is a Kasparov cycle if and are compact operators on . If is a prime C*-algebra, and is a linear map which is unital and surjective up to compact operators, and preserves Kasparov cycles in both directions, then the induced map is either a -automorphism or a -anti-automorphism. Our work extends the main result of [J. Math. Anal. Appl. 354 (2009), 625-629] to the set of Kasparov cycles, showing that the assumption `` has real rank zero’’ is redundant in our results.

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