We study gradient estimates and volume growth on locally finite weighted graphs satisfying the condition with . We establish a variational inequality for the heat semigroup and derive from it a family of Li-Yau type gradient estimates. Furthermore, under suitable assumptions on , we establish a uniform heat retention estimate for metric balls. Combined with a heat kernel Harnack inequality obtained from the established gradient estimate, this yields a curvature dependent exponential volume doubling estimate \begin{equation*} V(x,2r)\leq C e^{cKr^2}V(x,r). \end{equation*} When , the result reduces to a uniform volume doubling and further implies that the bottom of the spectrum of vanishes on infinite graphs.

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