Learning the generator of an open many-body system is more challenging than Hamiltonian learning: local responses, which can directly reveal coherent interaction terms in closed-system dynamics, may also contain dissipative contributions in open-system dynamics. In this paper, we address this challenge by developing an efficient Lindbladian learning framework for a known local candidate generator dictionary with bounded dissipative support and either bounded dual-interaction-graph degree or bounded unweighted local strength. The framework resolves the coherent-dissipative ambiguity by treating local Pauli responses as a linear system over both types of generator terms. Inverting this response system separates their contributions and makes the individual Lindbladian coefficients accessible from local response data in a fixed short-time window. Within this framework, we develop two efficient learning algorithms: Chebyshev–Lobatto response interpolation, which uses logarithmically many short evolution times and has a post-mean cost linear in , with the stated dependence on , and Single-time projected response contraction, which uses a single fixed evolution time and globally inverts a truncated response function. Both procedures estimate candidate coefficients to entrywise accuracy using sample and classical post-processing complexity. Our theoretical results establish local response inversion as a scalable paradigm for learning, calibrating, and diagnosing complex quantum systems from experimentally accessible short-time data.

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