We generalize Tweed’s seminal Born~I formalism for the electron-impact double ionization of two-electron atomic systems (, , ) to non-extensive plasma environments described by Tsallis -statistics. The bare Coulomb interaction is replaced by a -deformed screened potential, which introduces a unique form factor envelope into the momentum-transfer integrations. We rederive the differential, partial, and total cross sections, demonstrating that this screening regularizes the classical high-energy Bethe logarithm and, in the regime, induces diffraction-like oscillations in the angular cross sections. The model is calibrated against digitized historical experimental data to quantify how non-extensive screening deforms the vacuum baseline. Finally, coupling these cross sections to a -Maxwellian distribution yields the macroscopic rate coefficients and reveals a novel subextensive critical-temperature threshold below which ionization is energetically forbidden.

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